The Nebraska Symphony Chamber Orchestra (NSCO) is comprised of professional musicians from the Lincoln and Omaha areas, and has performed for the annual production of the Lincoln Midwest Ballet Company's Nutcracker at the Lied Center for Performing Arts since 1995. The NSCO has also performed for operas, musical productions and a variety of special events for Nebraska Wesleyan University, Doane College and area churches. In 1994, the NSCO performed with Rod Stewart in a sold out performance at Lincoln's Devaney Center.

In the last several years, the NSCO has performed Bach's Magnificat, Handel's Messiah, and Vivaldi's Gloria. In addition, the NSCO has provided local musicians for the National Touring Productions of Ragtime, Chicago, All Shook Up, South Pacific, Peter Pan, Frankie Avalon, Steve Lippia-Simply Sinatra, Broadway Today, Celtic Tenors, Bernadette Peters, All Hands On Deck, Sandy Hackett's Rat Pack Show, Ain't Misbehavin' and A Gentleman's Guide to Love and Murder.